A Visual Guide to Scleroderma and Approach to Treatment by Maureen D. Mayes

By Maureen D. Mayes

A visible advisor to Scleroderma and method of remedy bargains a targeted research of the prognosis and administration of scleroderma. particularly designed to enlighten and replace scholars and trainees, practising rheumatologists and basic practitioners at the quite a few varieties of systemic sclerosis, the ebook is designed to be an simply available software that still covers power issues and the newest remedy advancements. a visible advisor to Scleroderma and method of remedy emphasizes attractiveness of universal medical positive aspects by means of targeting and illustrating critical and not more serious types of the ailment that could contain inner organs resembling the gastrointestinal tract, center, lungs and kidneys. images and radiographs introduce every one bankruptcy and are observed by way of a advisor to workup and remedy. A accomplished and valuable addition to the literature, this article isn't just an important source for college kids, trainees and first care physicians; it's going to even be of important curiosity to experts within the fields of rheumatology, dermatology, pulmonology, cardiology, gastroenterology and nephrology.

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Herrick Fig. 20 Abnormal capillaries by videocapillaroscopy (Â300 magnification) with areas of avascularity, some distortion of the normal capillary architecture and one angiogenic (“bushy”) capillary [Copyright Salford Royal NHS Foundation Trust] Fig. 21 Photograph of the hand from the subject in Fig. 20 showing flexion deformities of the fingers and healing ulcers resulting in impairment in hand function [Copyright Salford Royal NHS Foundation Trust] Case 11 Scenario: A 39-year-old female with diffuse cutaneous SSc and severe digital vasculopathy with recurrent digital ulceration (ANA of 1:1,000 with a positive anti Scl-70 antibody).

Localized scleroderma. Curr Opin Rheumatol. 2006;18(6):606–13. 3. Zwischenberger BA, Jacobe HT. A systematic review of morphea treatments and therapeutic algorithm. J Am Acad Dermatol. 2011;65(5):925–41. 4. Nezafati KA, Cayce RL, Susa JS, Setiawan AT, Tirkes T, Bendeck SE, Jacobe HT. 14-MHz ultrasonography as an outcome measure in morphea (localized scleroderma). Arch Dermatol. 2011;147(9):1112–5. 5. Chiu YE, Vora S, Kwon EK, Maheshwari M. A significant proportion of children with morphea en coup de sabre and Parry-Romberg syndrome have neuroimaging findings.

This is an early pattern with a small number of giant capillaries and hemorrhages but no obvious loss of capillaries and relatively well-preserved capillary architecture [Copyright Salford Royal NHS Foundation Trust] Nailfold capillaroscopy (widefield technique) (Fig. 3) was abnormal with areas of angiogenesis (also described as “bushy,” “ramified,” “arborized” capillaries). These appearances are characteristic of patients with a myositic component to their disease [3]. Gottron’s papules (erythematous, raised papules over the metacarpal and interphalangeal joints) were seen on physical examination in keeping with an overlap with dermatomyositis (Fig.

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