AIDS-Associated Viral Carcinogenesis by C. Meyers

By C. Meyers

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In a retrospective study by Loi and colleagues,242 11 patients, ten of whom were already on HAART prior to chemotherapy, were treated mostly with cyclophosphamide and chorambucil, combined with prednisolone. 2 months. Mortality from MCD and its resulting complications was 45% in this series. Steroids are generally used along with chemotherapy, thus results are limited in treatment for MCD. 226 42 AIDS-Associated Viral Oncogenesis Antiviral Therapy Inconsistent results have been reported in various studies from the use of antiviral therapy targeting HHV-8.

2. AIDS MALIGNANCIES ANITA ARORA, MD*, ELIZABETH CHIAO, MD*, AND STEPHEN K. TYRING, MD, PHD† * † Center for Clinical Studies, Houston,TX University of Texas Health Science Center, Houston,TX INTRODUCTION Malignancies were one of the earliest recognized manifestations that lead to the eventual description of the acquired immune deficiency syndrome (AIDS) epidemic. Kaposi’s sarcoma (KS), a rare skin cancer primarily seen in elderly men prior to the epidemic, became one of the first entities described in association with AIDS.

Mortality from MCD and its resulting complications was 45% in this series. Steroids are generally used along with chemotherapy, thus results are limited in treatment for MCD. 226 42 AIDS-Associated Viral Oncogenesis Antiviral Therapy Inconsistent results have been reported in various studies from the use of antiviral therapy targeting HHV-8. For instance, remission of HIV-associated MCD, along with a decline in plasma HHV-8 DNA levels, was attained in three patients treated with intravenous ganciclovir therapy.

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